盐酸坦洛新并输尿管镜碎石术对输尿管结石的效果(1)
[摘要] 目的 观察盐酸坦洛新联合输尿管镜碎石术对输尿管下段结石的临床治疗效果。
方法选取输尿管结石病人134例，随机分为输尿管镜碎石术组(对照组)和盐酸坦洛新联合输尿管镜碎石术组(观察组)，每组67例。应用视觉模拟量表(VAS)评定两组术后疼痛程度，比较两组手术时间、住院时间、术后并发症发生率以及临床疗效。
結果观察组VAS评分显著低于对照组(t=2.553，P<0.05)，两组手术时间和住院时间比较差异无显著性(P>0.05)。观察组结石排除有效率为92.5%(62/67)，显著高于对照组80.6%(54/67)(χ2=2.462，P<0.05)。观察组血尿、腰痛和发热发生率分别为77.6%、20.9%和16.4%，显著低于对照组的95.5%、38.8%和35.8%(χ2=2.512～2.564，P<0.05);观察组恶心呕吐不良反应发生率为6.0%，与对照组比较差异无显著性(P>0.05)。
结论
盐酸坦洛新联合输尿管镜碎石术可显著提高单纯手术治疗的临床疗效，有利于减少病人术后并发症。
[关键词] 盐酸坦洛新;输尿管镜检查;输尿管结石;治疗结果
[中图分类号] R693.4
[文献标志码] A
[文章编号] 2096-5532(2019)01-0111-03
CLINICAL EFFECT OF TAMSULOSIN HYDROCHLORIDE COMBINED WITH URETEROSCOPIC LITHOTRIPSY IN TREATMENT OF URETERAL CALCULI
YE Zhihua， WANG Xiaoying， HUANG Geng
(Department of Urinary Surgery， Huangshi Center Hospital， Hubei Huangshi 435000， China)
[ABSTRACT]ObjectiveTo investigate the clinic effect of tamsulosin hydrochloride combined with ureteroscopic lithotripsy in the treatment of lower ureteral calculi.
MethodsA total of 134 patients with ureteral calculi were enrolled and randomly divided into ureteroscopic lithotripsy group (control group with 67 patients) and tamsulosin hydrochloride+ureteroscopic lithotripsy group (observation group with 67 patients). Visual Analogue Scale (VAS) was used to evaluate pain after surgery， and the two groups were compared in terms of time of operation， length of hospital stay， postoperative complications， and clinical outcome.
ResultsThe observation group had a significantly lower VAS score than the control group (t=2.553，P<0.05)， and there were no significant differences in time of operation and length of hospital stay between the two groups (P>0.05). The observation group had a significantly higher response rate for calculus expulsion than the control group (92.5% (62/67) vs 80.6% (54/67)，χ2=2.462，P<0.05). The observation group had significantly lower incidence rates of hematuria， low back pain， and pyrexia than the control group (77.6%/20.9%/16.4% vs 95.5%/38.8%/35.8%，χ2=2.512-2.564，P<0.05). There was no significant difference in the incidence rate of nausea and vomiting between the observation group and the control group (6.0% vs 4.5%，P>0.05).
ConclusionTamsulosin hydrochloride combined with ureteroscopic lithotripsy has a better clinical effect than surgical treatment alone and can reduce postoperative complications. Therefore， it holds promise for clinical application., http://www.100md.com(叶志华 王小英 黄耿)
方法选取输尿管结石病人134例，随机分为输尿管镜碎石术组(对照组)和盐酸坦洛新联合输尿管镜碎石术组(观察组)，每组67例。应用视觉模拟量表(VAS)评定两组术后疼痛程度，比较两组手术时间、住院时间、术后并发症发生率以及临床疗效。
結果观察组VAS评分显著低于对照组(t=2.553，P<0.05)，两组手术时间和住院时间比较差异无显著性(P>0.05)。观察组结石排除有效率为92.5%(62/67)，显著高于对照组80.6%(54/67)(χ2=2.462，P<0.05)。观察组血尿、腰痛和发热发生率分别为77.6%、20.9%和16.4%，显著低于对照组的95.5%、38.8%和35.8%(χ2=2.512～2.564，P<0.05);观察组恶心呕吐不良反应发生率为6.0%，与对照组比较差异无显著性(P>0.05)。
结论
盐酸坦洛新联合输尿管镜碎石术可显著提高单纯手术治疗的临床疗效，有利于减少病人术后并发症。
[关键词] 盐酸坦洛新;输尿管镜检查;输尿管结石;治疗结果
[中图分类号] R693.4
[文献标志码] A
[文章编号] 2096-5532(2019)01-0111-03
CLINICAL EFFECT OF TAMSULOSIN HYDROCHLORIDE COMBINED WITH URETEROSCOPIC LITHOTRIPSY IN TREATMENT OF URETERAL CALCULI
YE Zhihua， WANG Xiaoying， HUANG Geng
(Department of Urinary Surgery， Huangshi Center Hospital， Hubei Huangshi 435000， China)
[ABSTRACT]ObjectiveTo investigate the clinic effect of tamsulosin hydrochloride combined with ureteroscopic lithotripsy in the treatment of lower ureteral calculi.
MethodsA total of 134 patients with ureteral calculi were enrolled and randomly divided into ureteroscopic lithotripsy group (control group with 67 patients) and tamsulosin hydrochloride+ureteroscopic lithotripsy group (observation group with 67 patients). Visual Analogue Scale (VAS) was used to evaluate pain after surgery， and the two groups were compared in terms of time of operation， length of hospital stay， postoperative complications， and clinical outcome.
ResultsThe observation group had a significantly lower VAS score than the control group (t=2.553，P<0.05)， and there were no significant differences in time of operation and length of hospital stay between the two groups (P>0.05). The observation group had a significantly higher response rate for calculus expulsion than the control group (92.5% (62/67) vs 80.6% (54/67)，χ2=2.462，P<0.05). The observation group had significantly lower incidence rates of hematuria， low back pain， and pyrexia than the control group (77.6%/20.9%/16.4% vs 95.5%/38.8%/35.8%，χ2=2.512-2.564，P<0.05). There was no significant difference in the incidence rate of nausea and vomiting between the observation group and the control group (6.0% vs 4.5%，P>0.05).
ConclusionTamsulosin hydrochloride combined with ureteroscopic lithotripsy has a better clinical effect than surgical treatment alone and can reduce postoperative complications. Therefore， it holds promise for clinical application., http://www.100md.com(叶志华 王小英 黄耿)
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